I read this story today about a man with type one diabetes who has controlled it for 85 years with a low-carb diet.
This article asks why children are hitting puberty earlier and earlier, with some girls menstrating at 6 or younger! Scientists say that some consequences of early puberty include obesity, reproductive cancer, depression, and anxiety. The average age of puberty for American girls has gone from 17 in the 19th century to about 8.
To contrast, the average age of sexual maturation in hunter-gatherers is from 15-18 years.