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Proton Pump Inhibitors Suck
In news from stupid-land: The FDA cautions against high dosages or prolonged use of acid inhibitors.
It's kind of criminal that these medicines are still in use, given that the latest studies published in journals show that the cause of GERD is not too much acid. So while proton pump inhibitors might mask the symptoms, they get rid of stomach acid, which we kind of evolved for a reason- to help digest food and to protect against pathogens.
The agency said it would order revised labeling on packages of the drugs to reflect the fact that they have been associated with an increased risk of fractures of the hip, wrist and spine…The drugs have previously been linked to an increased risk of contracting pneumonia and the troublesome bacterium Clostridium difficile, as well as to an increased risk of dementia. A recent study found that the drugs increase the risk of bone fractures by about a quarter. It is not clear what the mechanism of the increased fractures is. Most researchers believe it is due to decreased absorption of calcium from the diet because of the reduced stomach acid, but it is possible that the drugs interfere with bone maintenance.
I am particularly incensed because last year my younger sister started having problems with GERD. She is only 19 and the doctor's recommended Prilosec. Instead she is now paleo and her symptoms have resolved. It's lucky that she knew that the paleo diet could treat GERD and she didn't get on the PPI wagon of dooooom like I did. Here is what I can remember:
It started when I was 18 or so. I was overweight and had terrible stomach problems. My internist gave me Zantec but my mom thought it was unnecessary and I never took it. Over the next two years I lost some weight on a vegetarian and then vegan diet, but the heartburn just got worse and worse. I couldn't sleep or concentrate on my school work. My school doctor finally convinced me to get on Prilosec. The spiel for these pills is that you take them for a month and it helps heal your esophagus, but of course it never works. I try to go off them after a month and the heartburn returns with a vengeance.
So I stay on them, but my IBS just gets worse. My allergist, who is treating me for severe asthma gives me an anti-spasmodic for my IBS and tells me not to worry about the PPIs. He says I'll probably be on them for the rest of my life, but not to worry since they are mostly harmless. At least I can eat pizza as much as I want now...
At some point I get really really sick. My doctor at school thinks it's just my IBS, but when I collapse and end up in the E.R. I finally get diagnosed with chronic salmonella. What should have been a one day bout of food poisoning decided to settle down in my weak digestive system. I take heavy antibiotics and recover...sort of. Now pretty much EVERYTHING upsets my stomach and even worse....I get chronic burping "attacks" all the time. I'm sickly in general- I get yeast, urinary tract, and sinus infections constantly. I get tested for all sorts of things like celiac and Crohns, but no dice. I do some research and find that PPIs might be causing some of my problems. Through looking at Pubmed I find out about a small study that effectively treated GERD with a low-carb diet. I try that for awhile, but using foods at the dorm cafeteria. I just end up feeling crappy... and no wonder with the factory farmed meat and gluten-laced sauces.
When I encounter Art De Vany's site through Marginal Revolution, I am intrigued by a more vegetable-heavy version of low-carb. I try it and it helps my IBS, but I'm still on the PPIs. When I try to go off I feel really terrible. I find a site where people tout apple cider vinegar as a cure. I start eating mostly paleo and taking apple cider vinegar diluted in water after every meal. I start eating a wide variety of vegetables and trying fish for the first time. It's not perfect, but I'm finally at the point where I can at least function without PPIs. I do an egg fast for a week. It takes about six months, mostly very low carb, but eventually I find myself...not taking any medicines at all.
A journey to get rid of heartburn fixed much more than that. At my worst I was on thirteen different medications and dependent on antibiotics every month. I haven't taken antibiotics in two years now...nor had to go to the doctor for IBS, GERD, or asthma. PPIs are hard to kick, but it was worth it.
My sister and my father have been sucessful with this approach as well, though they were lucky that they never took PPIs. PPIs alter your digestive system and it can be hard to get it in working order again.
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This blog is about the intersection between evolutionary biology and food. But also about practical applications, sustainable agriculture, and general tasty things. I originally started eating this way to heal from chronic health problems and...it worked!
Comments
"the latest studies published
"the latest studies published in journals show that the cause of GERD is not too much acid."
what is the cause??
It seems to have an
It seems to have an autoimmune component.
Hey Melissa Love your blog
Hey Melissa
Love your blog and wow, you got the shit kicked out of your digestive system!
As a former raw vegan ( my blog on that is www.debbiedoesraw.blogspot.com) and a now more Paleo type grass fed momma, my tummy has never been happier.
Let me just say that when I went raw, the dog was often put to shame by the gas I emitted.. and the painful burping, stomach aches, bloating... no thanks !!
Cooking is good.
I like feeling human again.
keep up the good work!
deb
Almost same experience for
Almost same experience for me....vis a vis asthma and allergies, not digestion.
While I was never a vegan, I was brainwashed by popular media and big pharma/food manufacturer's and Government non-profit PSA propaganda to believe the lies that meat and saturated fats were bad for you. So I ate as vegetarian as possible...oftentimes, three or four days straight of eating nothing but plant foods - poi, banannas, nuts, legumes, fruits and salads...as well as "whole grain" everything. When I did eat animal based foods, I always ate lean/non-fat/low-fat/lite etc.
Non-dairy creamers. Turkey bacon. Margarine. Ground turkey instead of ground beef. Non-fat sour cream and yogurt. Always lean cuts of meat, if I did eat meat. Low-fat cheese. Non-stick cooking sprays for cooking. "No cholesterol" canola oil, etc.
Eating like this for over 5 years saw my waistline continue to expand and my asthma to be perpetually aggravated and chronic.
Doctors eventually put me on inhaled steroid combo drug. It was like a miracle...my asthma was gone.
But I still kept getting fatter, despite following the conventional wisdom of "eating healthy." Oh...and I've been an exercise/physically demanding recreation guy (always doing something with an asthma inhaler in my pocket.) In other words, I regularly exercise...I have my entire adult life. And yet I was still losing the "battle of the bulge."
And than one day, I awoke with blurry vision.
At 32 years of age, I had developed cataracts.
In the fine print of the inhaled steroid's info insert, it stated that long term use has been shown to increase the likelihood of cataract formation. I saw four different doctors, and they were all dumbfounded that I could have gotten the cataracts from only about a year of being on the medication.
They told me I couldn't receive intra-ocular lens replacement surgery until my cataracts progressed to the point of being legally blind (it was a provision of my healthcare coverage plan). Within 6 months, my vision had degenerated to 20/400. Legally blind. I lived like that for 3 more months before finally got the surgery and can now see just fine.
Doctors insisted I should maintain my inhaled steroid medication. I told them no, I'd rather die of an asthma attack than to go blind again. I resisted the Doctors and just told them I'd stick to using my rescue inhaler whenever I felt an attack coming on. In the parlance of conventional medicine, this is not "controlling" my condition. But they couldn't force me to...so I never touched the steroid drugs again.
Shortly after this surgery, I came to the conclusion that I was at a crossroads - either I lose weight, or I'd have to buy an entirely new wardrobe. I was tipping the scale at 220...when I graduated from High School, I was 155.
I had to accept the notion that my low-fat, predominantly plant based diet and a lot of aerobic/endurance exercise was not helping me lose weight AT ALL.
So I turn to the internet and google up personal fitness trainers websites to read up on the topic of body building and losing weight. One of the nutrtionists I read up on was a guy named Mike Furci, and his reference material to back up his proscriptions were articles by Mary Enig and Sally Fallon at the WAPF. I begin reading everything at the WAPF site. The site hit a chord with me...especially when I read Dr. Price's observations of indigenous populations in Polynesia and their physical state on their native diets and how it degenerated into malnourishment after introduction to the Western hi-carb/grain-heavy diet. Looking at the number of fellow Hawaiians who are fat, obese, diabetic etc., I realize that Price's observations coincide precisely with the historical record of Western contact with the Hawaiian islands. Cook and his sailors made copious notes regarding the athletic physiques and giant stature and girth of the natives when they first landed here.
So I change my diet to a high saturated fat, high protein, no grain diet. Inside of 3 months, I'm down to 175 pounds...and can actually see my muscle structure. And than one day, I also realize that it's been quite some time since I had an asthma attack and needed my rescue inhaler. Well damn...wouldn't you know it - it appears my diet was a huge part of my asthma as well.
Such results drove me to research deeper into diet issues.
I now believe that the inhaled steroids combined with my high Omega-6 fatty acid imbalanced diet contributed to my cataract formation and chronic asthma. Had I been eating an Omega-3 rich diet (of which I learned accumulates especially in the eyes and the brain and lung tissue), I may not have developed the cataracts, and had I not been conditioned to believe that saturated fats were detrimental, I would not have had the chronic asthma that had me taking the steroids in the first place.
This is what makes me so irritated with the vegan/vegetarian claims of dietary superiority. Because I believed it, and tried to follow it as much as possible. I would regularly go to events/restaurants, and eat everything plant based, and leave the meat only partially eaten. Or I would order food specifically to avoid the meat and saturated fats, and I believed I was eating "healthy." The only reason I never tried full blown vegitarian-ism/vegan-ism is because I've been hunting pigs since my teens. I live the hunter's ethos of kill only what you will eat, and eat everything that you kill. But even after a successful hunt, I'd still cook up the pig and share it with as many people as possible and still try to eat more vegetables in proportion to the meat on my plate.
In short, I have a special loathing for the "plants are a superior food source" and that meat and animal fats are bad for you ideology, because by trying to apply it, it just gave me health problems.
The largest paradigm shift for me was the discovery that eating fat did not make you fat....but that's what one would believe if they mindlessly absorb the message of Americas corporate food processors and their ubiquitous marketing promotions based on low-fat/non-fat claims of health.
I'm now completely opposite in my approach, and I've never been healthier. Not only is my asthma very rare now (I still get allergic reactions to excessive dust exposure and animal dander), but I've never had better endurance when I engage in strenuous activity.
Praise the Lard!
Hi Melissa, That's quite a
Hi Melissa,
That's quite a story. Glad you figured things out. GI problems are one of the most quintessential facets of the "disease of civilization". They're almost totally absent in many non-traditional cultures: virtually no GERD, no appendicitis, no ulcers, no diverticulitis, no constipation, no hemorrhoids, no IBS, no colorectal cancer. Although some have high rates of stomach cancer. The usual explanations of high-fiber low-fat don't hold up, because the Inuit didn't have those problems either, not even constipation. Although I do think fermentable fiber is one piece of the puzzle.
http://thehealthyskeptic.org/
http://thehealthyskeptic.org/get-rid-of-heartburn-and-gerd-forever-in-th...
Great series on the topic.
Wow, what a story you've got.
Wow, what a story you've got. It makes me just rageful to read things like that. And people wonder why I have a bad attitude about allopathic medicine!?
So glad you found your way out.
I've never known before all
I've never known before all the reasons to take (and not take) PPIs. It sounds horrible what you went through. A doctor at school gave me a two weeks supply to help my body clear up a nasty stomach virus (it helped).
I started having bad stomach
I started having bad stomach pains in April, including GERD. It got to the point where all I could eat was yoghurt and dry toast. I lost almost 10 pounds. Finally went to the doctor and was told that I probably have an ulcer. He prescribed Protonix, another PPI. I took it for 3 days then stopped once I read about the longterm side effects.
So I decided to give paleo eating a go, along with probiotics, raw keffir and cabbage juice. And you know what? Two weeks later my stomach issues are GONE. I even had some spicy chili last weekend no problem. I really, really wish that doctors would help their patients explore these non-invasive options first before just handing out the questionable meds. It's just so terrible to have your system messed up by supposed medicine. Thanks for posting on this topic.
I agree. You are lucky you
I agree. You are lucky you didn't take them for long! It's so funny because spicy foods are blamed for GERD. They obviously can cause things to flare up, but they are probably not the cause. I'm soooooo happy that I can eat spicy foods as much as I want now!
I have to completely agree.
I have to completely agree. Spicy foods were one of the main things I missed during my time on Protonix after being diagnosed with GERD and IBS.
One thing that disturbed me about my gastroenterology specialist was that his prescription pad was actually printed with 4 different meds on it, including Protonix, with check boxes next to each. I imagine the situation is the same with many cardiologists and statin prescriptions. I guess some doctors are not concerned with discovering the underlying causes of an issue, just patching it up and seeing the next patient.
my husband has quit taking
my husband has quit taking zantac, which he took for over a decade, and finds that eating less wheat helps and taking apple cider vinegar in water helps, along with other lifestyle changes. it's insane that MDs have no problem rxing medicine for a condition that is directly caused by what we eat.
Thank you for your story.
Thank you for your story. WOW... You have been through the gauntlet of drugs too.
And SURVIVED.
QUOTE: "... stomach acid,
QUOTE:
"... stomach acid, which we kind of evolved for a reason- to help digest food and to protect against pathogens."
Until people understand science and evolution, medicine will continue to be not much more than magic potions. And that won't happen until ignorant people stop interfering with the teaching of science and evolution.
This is good information to
This is good information to know. I've had some sort of chronic upset-stomach issues for some time now. At my annual exam two years ago, my physician started me on a chronic prescription of prilosec - daily if needed. I've found that a few weeks of prilosec will help calm the tummy trouble, but it's better to just avoid foods that make my stomach upset in the first place.
I also have severe, chronic headaches. My neurologist would rather put me on three different medications (none of which eliminate the headaches, only make it possible for me to function) than find the cause.
I recently started attempting a primal/paleo diet, but I'm not 100% there yet. I'm hoping that a better diet will eliminate both headaches and tummy problems.
Great post, very nice to hear
Great post, very nice to hear that somehow you found out that the solution wasn't to be found in 'modern medicine' but in real food.
My mother has IBS but doesn't really want to try to go no-gluten or no-grains, and is still afraid of fat (when she sais something about high-fat, and looks at me, she says: "Oh, yeah, fat ain't bad, is it?", though.
My sisters little baby has quite serious eczema, but she is not open to a low-suger or low/no-grains test diet of 4 weeks. I can see why, because over here, nowadays it is 100% normal to feed your small kid grains, sugar infused yoghurts, and cookies every day in every day normal life. Although I already demonstrated that I lost weight on this diet/lifestyle and got 100% rid of my canker sores, amonght other issues, after 20+ years of doctors telling me: "We have no idea what triggers these sores, you are probably just low on vitamins or have a weak immune system or something like that". I just turned 34, but I think I have more years to go than 5 years ago (maybe even more?) at this time.
It's so hard to change people's beliefs, even if you show them an example in their personal social group. Peer pressure, and the almost 'sacred' status of the healthcare professionals really is deeply embedded in people's minds...
My roommate from last
My roommate from last semester has GERD... he was always having really uncomfortable burping attacks and other unfortunate stomach problems. I think he's going to have some sort of procedure done, but I wonder if he'll be warned to change his diet (lots and lots and lots of carbs). I'll be interested to see how he fares.